ProteoNic and Chr. Hansen Sign Service Agreement

ProteoNic, the protein expression experts, and Chr. Hansen, the Danish natural ingredient solution company, have signed a service agreement. The contract specifically includes construct design and cloning for applying its unique yield enhancement products. ProteoNic will also provide support in strain engineering to improve Chr. Hansen’s upstream production.

ProteoNic and Fraunhofer IME sign Research License and start collaboration on protein expression in

ProteoNic and Fraunhofer Institute of Molecular Biology and Applied Ecology (Fraunhofer IME) announce their collaboration regarding protein expression in plant systems. Fraunhofer IME has obtained a Research License to use ProteoNic’s UNic™ expression technology in a variety of its research projects. In addition, ProteoNic will support Fraunhofer IME by supplying its expertise and research services regarding translation optimization for the development of a plant expression system that produces antibodies at commercially relevant yields.

ProteoNic and Wageningen University and Research Centre, AFSG sign Research License and collaboration

Today ProteoNic and Wageningen University and Research Centre (Wageningen UR), Agrotechnology and Food Sciences Group announce their collaboration on the development and expression of enzymes in fungal host systems. ProteoNic has granted a Research License and will provide its expertise in construct design and protein expression optimization. Wageningen UR will apply ProteoNic’s UNic™ expression enhancement technology in projects in which industrial enzymes are expressed in fungal host systems.

ProteoNic broadens its UNic™ expression technology toolbox

ProteoNic is a supplier of specialized products and services in the field of expression enhancement founded on its leading expertise in optimizing messenger RNA usage. Today, ProteoNic is proud to announce it has launched UNic-YTee™, its yeast specific Translation Enhancement Element (TEE). UNic-YTee™ is part of the company’s existing UNic™ expression technology toolbox already covering mammalian, fungal and plant production host systems. The UNic™ products boost translation efficiency and are complementary to transcription enhancing and other common expression technologies. ProteoNic achieved solid proof of concept increasing expression yields up to a factor 7 in Saccharomyces cerevisiae for several commercially relevant proteins.

ProteoNic and ModiQuest announce collaboration

Today ProteoNic and ModiQuest announce their collaboration on antibody expression in mammalian cell culture for use in diagnostic and therapeutic product development and manufacturing. ProteoNic will provide its expertise in construct design and protein expression optimization. ModiQuest will apply its proprietary vectors systems and expertise in high throughput production of high level expressing mammalian cell lines in combination with the UNic™ expression technology to manufacture its commercial antibodies in mammalian cell lines.

ProteoNic presents at the Advanced International Biotechnology Courses

On March 30 – April 4 the “Advanced International Biotechnology Courses” will be held at the NH Leeuwenhorst Congres Centre in Noordwijkerhout and partially at the Leiden Bio Science Park, the Netherlands. In addition to sponsoring these full time, advanced professional courses, ProteoNic will give a lecture on “Upstream modification for enhanced production yield” on April 1, 2008 as part of the “Advances in Cell Culture” course. Other presenters include Xendo, Merck GmbH, Serono, BioCult and the University of Southern California.

ProteoNic announces collaboration with TNO

Today ProteoNic announces it has entered into a collaboration with TNO to further commercialize and validate ProteoNic’s UNic™ expression technology in mammalian host systems. ProteoNic will provide expertise in construct design and protein expression optimization. TNO will apply this expertise and the UNic™ expression technology to manufacture commercial proteins in CHO cell lines.

ProteoNic relocates its lab and offices

Today ProteoNic BV announces the relocation of its offices at the BIO Science Park in Leiden (The Netherlands) which will take place May 1, 2007. At the new location ProteoNic will be fully equipped to carry out its R&D activities further optimizing its UNic™ expression enhancement technology and the development of other products and technologies.

ProteoNic wins Draper Fischer Jurvetson investors pitch competition chaired by Tim Draper

ProteoNic BV was named best investors’ pitch by Tim Draper, founder and managing director of renowned American Venture Capitalist firm Draper Fischer Jurvetson. During the Holland Innovation conference in Utrecht, the Netherlands 20 selected early stage companies from the life science and high tech sectors like telecom, internet and IT were given the opportunity to pitch their proposition to Mr. Draper, Residex Venture Capital Network and Solid Ventures. The jury, chaired by Tim Draper, unanimously elected ProteoNic, one of the only two life science companies contending, as the number one pitch based on content, presentation and most promising proposition in a billion dollar market.

New collaboration

ARTES Biotechnology GmbH and ProteoNic BV start research collaboration Today ARTES Biotechnology GmbH, Germany, and ProteoNic B.V., the Netherlands, announce the start of their research collaboration.Both companies will join forces to investigate on the application of ProteoNic´s proprietary technology for enhancement of gene expression in the methylotrophic yeast Hansenula polymorpha, offered by ARTES.